منابع مشابه
Non-classical transcriptional regulation of HLA-G: an update
Human leucocyte antigen-G (HLA-G) plays a key role in maternal-foetal tolerance and allotransplantation acceptance and is also implicated in tumour escape from the immune system. The modulation of HLA-G expression can prove to be very important to therapeutic goals in some pregnancy complications, transplantation, cancer and possibly autoimmune diseases. In spite of substantial similarities wit...
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Since the publication of a critical review on ADHD neuroimaging in a past issue of this journal (Leo and Cohen, 2003), several relevant studies have appeared, including one study that had a subgroup of unmedicated ADHD children (Sowell, Thompson, Welcome, Henkenius, Toga, and Peterson, 2003). In this update to our earlier review we comment on this last study’s failure to report on the crucial c...
متن کاملHLA-G بررسی ساختار و عملکرد
HLA-G is a nonclassical HLA class Ib, which is located on chromosome 6 (6p.21.3). In contrast to HLA class I molecules, HLA-G has restricted polymorphism. Expression of this molecule in the physiological conditions limits to certain tissues such as thymus, cornea, nail matrix, trophoblast and pancreas. Up to now, 50 alleles of HLA-G molecules have been discovered with 16 distinct functional pro...
متن کاملHLA-G*0105N null allele encodes functional HLA-G isoforms.
Expression of the nonclassical HLA class I antigen, HLA-G, is associated with immune tolerance in view of its role in maintaining the fetus in utero, allowing tumor escape, and favoring graft acceptance. Expressed on invasive trophoblast cells, HLA-G molecules bind inhibitory receptors on maternal T lymphocytes and NK cells, thereby blocking their cytolytic activities and protecting the fetus f...
متن کاملNeonatal Sepsis: An Update
Sepsis is the most common cause of neonatal mortality. As per National Neonatal-Perinatal Database (NNPD), 2002-2003, the incidence of neonatal sepsis in India was 30 per 1000 live births. Signs and symptoms of sepsis are nonspecific; therefore empirical antimicrobial therapy is promptly initiated after obtaining appropriate cultures. The early manifestations of neonatal sepsis are vague and il...
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ژورنال
عنوان ژورنال: Tissue Antigens
سال: 2007
ISSN: 0001-2815,1399-0039
DOI: 10.1111/j.1399-0039.2006.00757.x